|
KMID : 0371420150890010017
|
|
Annals of Surgical Treatment and Research
2015 Volume.89 No. 1 p.17 ~ p.22
|
|
|
The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis
|
|
Eker Tevfik
Genc Volkan
Sevim Yusuf
Cumaogullari Ozge
Ozcelik Menekse
Kocaay Akin Firat
Ensari Cemal Ozben
Pasaoglu Ozge Tugce
|
|
|
Abstract
|
|
|
Purpose: The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses.
Methods: Forty male Wistar albino rats were used in the study and randomized into 4 groups. Ischemia-reperfusion models were built in groups 3 and 4. Jejunojejunostomy was performed in all rats and assigned to an oxygen/nitrous oxide mixture with a fraction of inspired oxygen of 30% in groups 1 and 3 and 80% in groups 2 and 4. The measurements of perianastomotic tissue oxygen pressure, bursting pressure, level of hydroxyproline were evaluated and compared in all groups.
Results: The perianastomotic tissue oxygen pressures, bursting pressures and levels of hydroxyproline were identified as significantly high in groups 2 and 4, administered a fraction of inspired oxygen of 80%, compared to groups 1 and 3, administered a fraction of inspired oxygen of 30%.
Conclusion: Perioperative supplemental oxygen contributes positively to the anastomotic healing.
|
|
|
KEYWORD
|
|
|
Anastomosis, Wistar rats, Oxygen
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|